Fracture Liaison Service: Impact on Subsequent Nonvertebral Fracture Incidence and Mortality

• DOI: 10.2106/jbjs.l.00223
• Publication Date: 2014-02-19T20:35:14Z
• Authors: Kirsten M.B Huntjens; Tineke A.C.M. van...; Joop P.W. van den...; Svenhjalmar van H...; Paul Willems; Bjorn Winkens; John A. Eisman; Piet P. Geusens; Peter R.G. Brink
• Keywords: Guideline

Background: A fracture liaison service model of care is widely recommended and applied, but data on its effectiveness are scarce. Therefore, the risk subsequent nonvertebral fractures mortality within two years after a was analyzed in patients who presented to hospital with without service. Methods: In 2005 2006, all consecutive an age fifty or older presenting were included. group that (the no-FLS group), only standard procedures followed address proper fracture-healing. FLS dual x-ray absorptiometry scans laboratory testing performed, if applicable, treated according Dutch guideline for osteoporosis. The using multivariable Cox regression models adjustments age, sex, baseline location. Results: total, 1412 (73.2% women, mean 71.1 years), 1910 underwent (69.8% 69.5 years). After adjustment location, attended had significantly lower (hazard ratio: 0.65; 95% confidence interval [CI]: 0.53 0.79) over follow-up. also group, this effect time-dependent, hazard ratio 0.84 (95% CI: 0.64 1.10) at twelve months 0.44 0.25 twenty-four months. Conclusions: Patients seen subsequently than those not service, reduction 35% 56%, respectively, appears be successful approach reduce number premature cohort patients. Level Evidence: Therapeutic III. See Instructions Authors complete description levels evidence.