Wait-and-See Policy as a First-Line Management for Extra-Abdominal Desmoid Tumors

• DOI: 10.2106/jbjs.m.00988
• Publication Date: 2014-04-16T19:53:31Z
• Authors: Sylvain Briand; Olivier Barbier; David Biau; Axelle Bertrand-V...; Frédérique Larous...; Philippe Anract; François Gouin
• Keywords: Watchful waiting; Conservative Management; Primary tumor

Extra-abdominal desmoid tumors are rare, locally aggressive neoplasms without metastatic potential. There is no clear consensus regarding their optimal management. The disappointing results of current treatments and the ability extra-abdominal to spontaneously stabilize have increasingly drawn interest toward conservative objective this study was evaluate a wait-and-see policy as first-line management for tumors.This two-center retrospective involved fifty-five patients with histologically proven tumor. primary outcome cumulative probability dropping out from policy. included symptoms. We conducted review relevant published series in which watchful-waiting strategy used.The 9.6% at time last follow-up. Spontaneous arrest tumor growth noted forty-seven (85%) over course study. Half were stabilized one year, potential increase beyond three years sporadic event (one case). Regrowth found two (4%).A an effective front-line or recurrent These tend spontaneously, on average after year evolution, failure approximately 10%.