Risk factors associated to diabetes in Mexican population and phenotype of the individuals who will convert to diabetes

• DOI: 10.21149/spm.v56i4.7351
• Publication Date: 2017-01-04T23:05:17Z
• Authors: Clicerio González...; Claudio Alberto D...; Mireya Zamora-Mac...; Belem Trejo-Valdivia; María Elena Gonzá...
• Keywords: Fasting glucose

Objective. To describe risk factors associated to the inci­dence of type 2 diabetes (T2D) in Mexican population and define phenotypic (clinical, anthropometric, metabolic) characteristics present individual who will convert diabetes, regardless time onset. Materials meth­ods. The Mexico City Diabetes Study began 1990, with 282 participants, had three subsequent phases: 1994, 1998, 2008. A systematic evaluation an oral glucose tolerance test was performed each phase. For diagnosis T2D, American Association criteria were used. Results. at 1939 individuals. Sub­jects converter stage (initially non diabetic that eventually converted T2D) had, baseline, higher BMI (30 vs 27), systolic blood pressure (119 116 mmHg), fasting (90 82mg/dl), triglycerides (239 196mg/dl), cholesterol (192 190mg/dl), compared sub­jects remained converters (p<0.05). Conclusion. phenotype described represents a potentially identifiable phase target for preventive intervention.