A Pioneering Study of Retinal Pigment Epithelial Photocoagulation to Seal Retinal Breaks and Prevent Hypotony during Pars Plana Vitrectomy

• DOI: 10.21203/rs.2.437/v1
• Publication Date: 2019-03-08T14:02:06Z
• Authors: XUN YANG; YOUYOU ZHA; SHU DU; XING CHEN
• Keywords: Retinal Tear

Abstract Background: During vitrectomy, a relatively high level of accuracy is required when using retinal laser energy, which difficult to control in the presence subretinal fluid and other conditions. We explored clinical effects pigment epithelium (RPE)photocoagulation closing breaks preventing hypotony during vitrectomy. describe possible indications RPE photocoagulation. Methods: This was prospective, non-random, uncontrolled case series study. recruited 20 patients, with detachment eyes. In this study, photocoagulation performed under detached retina holes. 3-4 rows at edge periphery around hole tear, replacing traditional part or all break. The energy 100-150mJ for 120-200ms seal breaks, same but little gaps without covering retina. Results: After 19 eyes, there visible pigmentation reaction except 1 eye located myelinated nerve fibre area. mean best-corrected visual acuity (BCVA) 6 months after surgery significantly higher than that before (p=0.002). At last follow-up, BCVA remained (p=0.001).There no significant difference between 6th month follow-up (p=0.806).The thickness neurosensory layer area 216.33±54.42μm 87.67±34.65μm, respectively. By end were serious complications, retinas eyes reattached. No occurred surgery. Conclusions: are similar breaks. sealed did not damage layer, still caused formation on RPE, resulting adhesion layer. Laser could be considered as comparable glue instead welding Trial registration ChiCTR1900021504,2019-02-24.