Corneal Cell Morphology in Keratoconus: A Confocal Microscopic Observation

• DOI: 10.21315/mjms2017.24.2.6
• Publication Date: 2017-04-25T00:58:07Z
• Authors: Somnath Ghosh; Haliza Abdul Mutalib; ; Sharanjeet Kaur; ; Rituparna Ghoshal; ; Shamala Retnasaba...
• Keywords: Scheimpflug principle

Purpose: To evaluate corneal cell morphology in patients with keratoconus using an vivo slit scanning confocal microscope.Methods: A cross-sectional study was conducted to the of 47 and 32 healthy eyes without any ocular disease.New different disease severities other co-morbidity were recruited from ophthalmology department a public hospital Malaysia June 2013 May 2014.Corneal evaluated slit-scanning microscope.Qualitative quantitative data analysed grading scale Nidek Advanced Visual Information System software, respectively.Results: The significantly that except endothelial density (P = 0.072).In group, increased level stromal haze, alterations such as elongation keratocyte nuclei clustering cells at anterior stroma, dark bands posterior stroma observed severity disease.The mean densities areas among stages < 0.001 P 0.044, respectively).However, changes endothelium not > 0.05) three keratoconus. Conclusion:Confocal microscopy observation showed significant keratoconic cornea normal cornea.Analysis also keratoconus.Understanding may help long-term monitoring management