T-Cell Lymphoblastic Lymphoma with Cutaneous Involvement in a Child: A Rare Case Report

• DOI: 10.2147/ccid.s376523
• Publication Date: 2022-09-23T06:10:05Z
• Authors: Jiaoquan Chen; Xin Tian; Nanji Yu; Liqian Peng; Huilan Zhu
• Keywords: Immunophenotyping; CD99; Lymphoblastic lymphoma; Rare disease

T-cell lymphoblastic lymphoma (T-LBL) is a heterogeneous malignancy derived from T-cells that more commonly affects teens and males. Most commonly, T-LBL exhibits signs of lymph nodes, bone marrow, mediastinal mass invasion, but in rare cases, the disease manifests cutaneously. We present case both cutaneous systemic presentation 9-year-old man which skin immunophenotype analysis showed TdT expression with positivity CD3, CD4 CD99. Review all currently described cases revealed most frequently positive tumor markers were (100%), CD3 (59.1%) CD99 (40.9%). Cutaneous involvement may be prognostic factor treating chemotherapy.