Cognitive fluctuations in connection to dysgraphia: a comparison of Alzheimer’s disease with dementia Lewy bodies

• DOI: 10.2147/cia.s79679
• Publication Date: 2015-03-27T16:03:31Z
• Authors: Emanuela Onofri; Marco Mercuri; Giuseppe Donato; Serafino Ricci
• Keywords: Dysgraphia; Cognitive test

Background: The purpose of the present study was to examine relationship between cognitive impairment and performance handwritten scripts presented as“letter-writing” a close relative by patients with dementia Lewy bodies (DLB), as fluctuations symptoms phase, in matched group Alzheimer’s disease (AD). degree writing disability personal, spatial, temporal orientation compared these two groups. Design methods: Fourteen simple questions, designed form that could be utilized any general practitioner order document level functioning each patient, were 30 AD 26 DLB patients. initial cognition test designated PQ1. examined on tests letter-writing ability. Directly after letter-writing, list 14 questions PQ1 again repeated procedure PQ2. difference measures (PQ1 – PQ2) DΔ. This ability administered over 19 days. Results: Several markedly strong relationships dysgraphia several observed, but deterioration from PQ2 all days significant not It is possible graphic expression even diagnosed moderate relatively severe there remains some residual capacity for understanding intention may expressed. Furthermore, differences noted due different speed at which process protein degradation occurs functional modification synapses. Conclusion: Our method can used part neuropsychological differentiate diagnosis DLB. Keywords: cognition, deficits, correlation,