Current Trends in Comorbidity Prevalence and Associated Mortality in a Population-Based Cohort of Hip Fracture Patients in Denmark

• DOI: 10.2147/clep.s410055
• Publication Date: 2023-07-18T07:15:08Z
• Authors: Pia Kjær Kristensen; Thomas Johannesso...; Morten Madsen; Alma B Pedersen
• Keywords: Hip Fracture

Background and Purpose: Patients with hip fractures often have comorbidities, but detailed data on comorbidity its impact prognosis are lacking. We described the current trends in prevalence of magnitude associated mortality. Methods: From Danish Multidisciplinary Hip Fracture Registry we included 31,443 fracture patients (diagnosed 2014– 2018). calculated individual diseases measured Charlson Comorbidity Index (CCI), Elixhauser Index, Rx-Risk Index. sex age-adjusted odds ratios (aORs) for 30-day mortality hazard (aHRS) one-year 95% confidence intervals (CI). Results: The most common identified CCI were cerebrovascular (18%), malignancies (17%), chronic pulmonary disease (14%), dementia (11%). Using hypertension (37%), cardiac arrhythmias (21%), fluid electrolyte disorders (15%) prevalent, while ischemic heart (42%), (39%), use antiplatelets (37%) prevalent when using only 28% had no compared to 38% 44% was stable through years. Compared comorbidity, very severe an aORs 2.6 (CI: 2.4– 2.9) CCI, 3.1) 3.1 2.7– 3.4) Interpretation: More than 50% moderate considerable variation between indices. varies considerably. All indices comparable dose-response associations These results relevant clinicians amend prevention target care, researchers decide which measure depending research question. Keywords: fracture, mortality,