Lung Features in Individuals with Biomass Smoke Exposure Characterized by CT Scan and Changes in Pulmonary Function

• DOI: 10.2147/copd.s325330
• Publication Date: 2021-09-10T09:10:08Z
• Authors: Jinglong Chen; Changbin Jiang; Youlan Zheng; Dongxing Zhao; Fan Wu; Zhuxiang Zhao; Jun Zhao; Qing Li; Bing Li; Gongyong Peng; Yumin Zhou; Pixin Ran
• Keywords: pulmonary function.; RC705-779; computed tomography; International Journal of Chronic Obstructive Pulmonary Disease; chronic obstructive pulmonary disease; 3. Good health; Diseases of the respiratory system; Pulmonary Disease, Chronic Obstructive; 03 medical and health sciences; 0302 clinical medicine; Pulmonary Emphysema; biomass smoke; Smoke; Humans; Female; Biomass; Tomography, X-Ray Computed; Lung; Original Research

Background and Objective: To determine the effects of BSE (biomass smoke exposure) on pulmonary non-pulmonary changes in patients with COPD compared normal individuals. Methods: Using a cohort, we recruited 16 healthy individuals (BSE normal), 19 BSE+COPD, 13 cigarette exposure (CSE 25 CSE+COPD, controls. Patients GOLD stage I II were included. Baseline data (demographic data, or CSE, lung function, CT findings) follow-up function collected. parameters emphysema, small vessels, airway remodeling, pectoralis muscles, erector spinae muscle measured. Results: Individuals mainly women (32/35, 91.43%). Compared CSE+COPD group, BSE+COPD group demonstrated slower decline, increased lower narrower lumen dimensions wall thickening moderate airways (all P < 0.05). controls, CSE groups exhibited significant reductions vessel area obvious remodeling ( showed significantly more severe emphysema as well reduced left major Conclusion: Healthy had evidence remodeling; area. Clinical Trial Registration: ChiCTR-OO-14004264. Keywords: biomass smoke, chronic obstructive disease, computed tomography,