<p>Visceral Fat Area, Not Subcutaneous Fat Area, is Associated with Cardiac Hemodynamics in Type 2 Diabetes</p>

• DOI: 10.2147/dmso.s284420
• Publication Date: 2020-11-16T20:49:17Z
• Authors: Yue Qiu; Xia Deng; Yujing Sha; Xunan Wu; Panpan Zhang; Ke Chen; Zhicong Zhao; Weiping Wei; Ling Yang; Guoyue Yuan; Li Zhao; Dong Wang
• Keywords: Subcutaneous fat; Epicardial Fat

Background: This study was conducted in patients with type 2 diabetes mellitus (T2DM) to assess the association between visceral fat area (VFA) and cardiac hemodynamics. Methods: A total of 568 (mean age 54± 12 years; 40.8% women) were enrolled. Visceral (VFA, m ) subcutaneous (SFA, evaluated by a bioelectrical impedance analyzer. Cardiac hemodynamics measured echocardiography, other clinical laboratory variables also assessed recorded. Patients divided into those VFA ≤ 100 (n=369) > (n=199). Results: VFA, SFA, LVMI (left ventricular mass index), left atrial diameter, diastolic diameter (LvDd), interventricular septal thickness (IVST), systolic (LvSd), posterior wall (PWT) levels high-V groups significantly higher than low-V groups. Correlation analysis showed that positively correlated ( r =0.120, p =0.004), LVM =0.249, < 0.0001), =0.375, aortic root =0.243, (LvSd) =0.211, 0.0001) negatively LVEF =− 0.107, =0.011). In multivariate linear regression analysis, strongest independent determinant β =0.04, =0.016), 0.01, =0.023), =0.035, Internal =0.014, LvSd =0.017, 0.0001). addition, better predicted cardiovascular disease risk AUC 0.609 (95% CI:0.563– 0.656), compared waist–hip ratio (WHR), statistically significant manner. Conclusion: We found correlation (but not SFA) hemodynamic parameters. The has advantages as predictor obesity is associated development factors (CVD) T2DM patients. Keywords: hemodynamics, index, mellitus,