Assessment of Cardiovascular Risk Factors and Their Interactions in the Risk of Coronary Heart Disease in Patients with Type 2 Diabetes with Different Weight Levels, 2013–2018

• DOI: 10.2147/dmso.s335017
• Publication Date: 2021-10-14T06:35:29Z
• Authors: Chenchen Wang; Demei Ye; Zuoling Xie; Xi Huang; Zheng Wang; Haiyan Shangguan; Wenwen Zhu; Shaohua Wang
• Keywords: Hyperlipidemia

Purpose: In addition to hyperglycemia and hyperlipidemia, obesity hypertension are important cardiovascular risk factors for coronary heart disease (CHD) in patients with type 2 diabetes mellitus (T2DM). This study aims explore the interaction of these factors. Patients Methods: Data hospitalized T2DM from 2013 2018 were collected. A multivariate logistic regression model was established. normal weight blood pressure recruited as controls. The on CHD evaluated by relative excess due (RERI). Results: Among 30,693 T2DM, 7202 (23.5%) had CHD. low group, prevalence nearly four times higher than that without (42.7% vs 11.3%, P < 0.01). OR value alone increased 1.29 (95% CI 1.06– 1.56) body mass index (BMI) 30.0– 34.9 kg/m group 1.35 1.11– 1.62) BMI ≤ 18.5 group. Additive observed between risk, especially (RERI:2.2, 95% 0.9– 3.5). showed a smile curve relationship. attributive proportion severe is, 0.52 0.35– 0.69) 0.18 − 0.59 0.95). Conclusion: Maintaining avoiding particularly co-occurring prevent Keywords: diabetes, cardiovascular, hypertension, index,