The Association Between Lipid Profile and Subfoveal Choroidal Thickness in Chinese Patients with Proliferative Diabetic Retinopathy Secondary to Type 2 Diabetes

• DOI: 10.2147/dmso.s419794
• Publication Date: 2023-08-17T04:20:12Z
• Authors: Chunyan Lei; Qibo Ran; Jianan Duan; Meixia Zhang
• Keywords: Lipid Profile; High-density lipoprotein

Extensive studies have studied the factors associated with subfoveal choroidal thickness (SFCT). However, of association between lipid profile and SFCT in patients proliferative diabetic retinopathy (PDR) type 2 diabetes remain limited. Thus, we aimed to investigate relationship PDR.This was a retrospective cross-sectional study. The included participants were inpatients who underwent vitrectomy for PDR contralateral eyes meeting criteria. Multivariate linear regression analysis used determine independent SFCT.A total 131 enrolled final analysis. average age 55.76 ± 9.88 years, 276.10 92.92 μm. model results showed that fully adjusted model, cholesterol, high-density lipoprotein cholesterol (HDL-C), low-density (LDL-C) had negative (β = -16.51, 95% CI: -29.57, -3.46; P 0.0148; β -42.65, -82.60, -2.70; 0.0390; -17.89, -33.24, -2.54; 0.0245, respectively), while triglyceride not significantly 5.23, -18.57, 29.02; 0.6678). Furthermore, stratified except triglyceride, trends HDL-C, LDL-C, consistent among different stratifications participants.The significant Chinese patients, but SFCT. This suggests these systemic imbalances contribute changes, often coexist patients.