Staphylococcus aureus Nasal Colonization in Spanish Children. The COSACO Nationwide Surveillance Study

• DOI: 10.2147/idr.s282880
• Publication Date: 2020-12-22T21:44:41Z
• Authors: Teresa del Rosal; Ana Méndez-Echeva...; Cesar Garcia-Vera; Luis Escosa-Garcia; Martin Agud; Fernando Chaves; Federico Román; José Gutierrez-Fe...; Enrique Ruiz de G...; Guillermo Ruiz-Ca...; Maria del Carmen ...; Albert Bernet; Sara Maria Quevedo; Ana Maria Fernánd...; Jesús Díez-Sebastian; Cristina Calvo
• Keywords: Mupirocin

To assess the prevalence and risk factors for S. aureus methicillin-resistant (MRSA) nasal colonization in Spanish children.Cross-sectional study of patients <14 years from primary care centers all over Spain. Clinical data aspirates were collected March to July 2018.A total 1876 enrolled. Prevalence MRSA 33% (95% CI 30.9-35.1) 1.44% 0.9-2), respectively. Thirty-three percent children (633/1876) presented chronic conditions, mainly atopic dermatitis, asthma and/or allergy (524/633). Factors associated with age ≥5 (OR 1.10, 95% 1.07-1.12), male sex 1.43, 1.17-1.76), urban setting 1.46, 1.08-1.97) presence asthma, dermatitis or allergies 1.25; CI: 1.093-1.43). Rural residence was only factor 3.62, 1.57-8.36). more frequently resistant than methicillin-susceptible ciprofloxacin [41.2% vs 2.6%; p<0.0001], clindamycin [26% 16.9%; p=0.39], mupirocin [14.3% 6.7%; p=0.18]. None strains tetracycline, fosfomycin, vancomycin daptomycin.The main are being above five age, gender, allergy, areas. is low, but higher other European countries rural settings.