Biological activity of green-synthesized silver nanoparticles depends on the applied natural extracts: a comprehensive study

• DOI: 10.2147/ijn.s122842
• Publication Date: 2017-01-31T02:34:43Z
• Authors: Andrea Rónavári; Dávid Kovács; Nóra Igaz; Csaba Vágvölgyi; Imre Boros; Zoltán Kónya; Ilona Pfeiffer; Mónika Kiricsi
• Keywords: Silver nanoparticle

Due to obvious disadvantages of the classical chemical methods, green synthesis metallic nanoparticles has attracted tremendous attention in recent years. Numerous environmentally benign methods have been developed yielding via low-cost, eco-friendly, and simple approaches. In this study, our aim was determine suitability coffee tea extracts silver as well compare performance obtained materials different biological systems. We successfully produced (C-AgNP GT-AgNP) using extracts; moreover, based on comprehensive screening, we delineated major differences activity C-AgNPs GT-AgNPs. Our results indicate that although GT-AgNPs exhibited excellent antimicrobial against all examined microbial pathogens, these particles were also highly toxic mammalian cells, which limits their potential applications. On contrary, manifested substantial inhibitory action tested microbes but nontoxic human mouse indicating an outstanding capacity discriminate between pathogens cells. These clearly show various used for stabilization reduction metal ions a defining role determining fine-tuning nanoparticles.