Fungus-mediated biological synthesis of gold nanoparticles: potential in detection of liver cancer

• DOI: 10.2147/ijn.s23195
• Publication Date: 2011-10-12T03:12:06Z
• Authors: Mohammad Owais; Arun Chauhan; Tufail; Sherwani; Mohammad Sajid; C Raman Suri; Mohammed Owais
• Keywords: Nanomaterials

Background: Nanomaterials are considered to be the pre-eminent component of rapidly advancing field nanotechnology. However, developments in biologically inspired synthesis nanoparticles still their infancy and consequently attracting attention material scientists throughout world. Keeping mind fact that microorganism-assisted is a safe economically viable prospect, current study we report Candida albicans -mediated biological gold nanoparticles. Methods results: Transmission electron microscopy, atomic force various spectrophotometric analyses were performed characterize The morphology synthesized particles depended on abundance C. cytosolic extract. nanophox particle analysis, microscopy revealed size spherical range 20–40 nm nonspherical found 60–80 nm. We also evaluated potential biogenic probe liver cancer cells by conjugating them with cell surface-specific antibodies. antibody-conjugated bind specifically surface antigens cells. Conclusion: this could successfully differentiate normal populations from cancerous Keywords: nanoparticles, , biomimetic synthesis, diagnosis, antiliver antibody