Biosynthesis of silver nanoparticles using Acacia leucophloea extract and their antibacterial activity

• DOI: 10.2147/ijn.s61779
• Publication Date: 2014-05-16T00:34:42Z
• Authors: Senbagam Duraisamy; Murugan Kasi; Senthilkumar Bala...; Saleh Al-Sohaibani
• Keywords: Silver nanoparticle; Nanobiotechnology; Silver nitrate

The immense potential of nanobiotechnology makes it an intensely researched field in modern medicine. Green nanomaterial synthesis techniques for medicinal applications are desired because their biocompatibility and lack toxic byproducts. We report the byproducts free phytosynthesis stable silver nanoparticles (AgNPs) using bark extract traditional plant Acacia leucophloea (Fabaceae). Visual observation, ultraviolet-visible spectroscopy, transmission electron microscopy (TEM) were used to characterize synthesized AgNPs. visible yellow-brown color formation surface plasmon resonance at 440 nm indicates biosynthesis AgNP. TEM images show polydisperse, mostly spherical AgNP particles 17-29 nm. Fourier transform infrared spectroscopy revealed that primary amines, aldehyde/ketone, aromatic, azo, nitro compounds A. may participate bioreduction capping formed X-ray diffraction confirmed crystallinity vitro agar well diffusion method antibacterial activity AgNPs against common bacterial pathogens Staphylococcus aureus (MTCC 737), Bacillus cereus 1272), Listeria monocytogenes 657), Shigella flexneri 1475). This research combines inherent antimicrobial metals with extract, yielding activity-enhanced new biomimetic approach (A. leucophloea) barks synthesize biocompatible could easily be scaled up additional biomedical applications. These polydisperse green-synthesized via can readily many not requiring high uniformity particle size or shape.