<p>Physiological Vibration Acceleration (Phybrata) Sensor Assessment of Multi-System Physiological Impairments and Sensory Reweighting Following Concussion</p>

03 medical and health sciences 0302 clinical medicine Evidence and Research [Medical Devices] Original Research 3. Good health
DOI: 10.2147/mder.s279521 Publication Date: 2020-12-07T22:04:59Z
ABSTRACT
To assess the utility of a head-mounted wearable inertial motion unit (IMU)-based physiological vibration acceleration ("phybrata") sensor to support clinical diagnosis concussion, classify and quantify specific concussion-induced system impairments sensory reweighting, track individual patient recovery trajectories.Data were analyzed from 175 patients over 12-month period at three sites. Comprehensive concussion assessments first completed for all patients, followed by testing with phybrata sensor. Phybrata time series data spatial scatter plots, eyes open (Eo) closed (Ec) powers, average power (Eo+Ec)/2, Ec/Eo ratio, time-resolved spectral density (TRPSD) distributions, receiver operating characteristic (ROC) curves are compared individuals no objective those clinically diagnosed concussions accompanying vestibular impairment, other neurological or both impairments. Finally, pre- post-injury case report results presented participant who was subsequently monitored during treatment, rehabilitation, return-to-activity clearance.Phybrata demonstrate distinct features patterns discernable impairments, pathology, pathology. ROC indicate that (Eo+Ec)/2 may be utilized while Eo as independent measures confirm respectively. All 3 area under curve (AUC), sensitivity, specificity above 90% their respective diagnoses. analyses quantifying severity subsequent monitoring improvements throughout treatment rehabilitation.Phybrata assists provides an important adjunct standard assessment tools objectively ascertaining guiding targeted rehabilitation strategies, recovery, assisting return-to-sport/work/learn decision-making.
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