Association of Excessive Daytime Sleepiness with Cerebral Small Vessel Disease in Community-Dwelling Older Adults

• DOI: 10.2147/nss.s357586
• Publication Date: 2022-04-21T09:50:26Z
• Authors: Jing Zhao; Qianqian Kong; Minghuan Wang; Hao Huang; Xirui Zhou; Yinping Guo; Yi Zhang; Lingshan Wu; Zhiyuan Yu; Xiang Luo
• Keywords: Epworth Sleepiness Scale

Excessive daytime sleepiness (EDS) and cerebral small vessel disease (CSVD) are common problems among older adults; however, their association is not clear. The present study aimed to investigate the frequency of EDS in CSVD patients relationship between neuroimaging markers CSVD.We conducted a cross-sectional 1076 community-dwelling adults aged 55-85 years. was measured using Epworth Sleepiness Scale (ESS), defined as an ESS score greater than 10. Binary logistic regression performed assess CSVD.Of participants (mean age: 65.58 ± 6.46 years, 60.5% female), prevalence 10.0%. more frequent with total sample (20.0% vs 10.0%, p <0.001). In fully adjusted models, significantly correlated burden (OR = 1.39, 95% CI 1.16 1.68, <0.001), severity white matter hyperintensities (WMH) 1.33, 1.14 1.54, presence lacunes 2.47, 1.53 4.00, <0.001) but microbleeds (CMBs) (OR=1.54, 0.92 2.56, 0.099) or enlarged perivascular spaces (EPVS) basal ganglia 1.16, 0.70 1.92, 0.564).We found high symptoms individuals. Further, associated WMH, lacunes, burden. Our findings further suggest may exhibit abnormal sleep-wake patterns.