Reproducibility of retinal circulation measurements obtained using laser speckle flowgraphy-NAVI in patients with glaucoma

• DOI: 10.2147/opth.s22093
• Publication Date: 2011-08-18T23:52:48Z
• Authors: Toru Nakazawa; Naoko Aizawa; Yu Yokoyama; Naoki Chiba; Kazuko Omodaka; Masayuki Yasuda; Takaaki Otomo; Nakamura; Nobuo Fuse
• Keywords: Optic disc; Optic disk

Laser speckle flowgraphy (LSFG) enables noninvasive quantification of the retinal circulation in glaucoma patients. In this study, we tested intrasession reproducibility LSFG-NAVI, a modified LSFG technique.Sixty-five eyes from 33 subjects (male (M):female (F) = 17:16) with mean age 49.4 ± 11.2 years were examined study. Two parameters indicating - coefficient variation (COV) and intraclass correlation (ICC) analyzed three times on same day that blur rate (MBR) was measured using LSFG-NAVI. The sites artery vein, optic disk, choroid. Following classification according to Glaucoma Hemifield Test (GHT; SITA-Standard 30-2 program), COV ICC patients (GHT+; 38 eyes, M:F 20:18, average 48.9 12.8 years) without (GHT-; 27 13:14, 50.1 8.7 abnormal glaucomatous visual fields.FOR ALL SUBJECTS, THE INTRASESSION REPRODUCIBILITY OF MBR IN OPTIC DISK (COV: 3.4 2.0; ICC: 0.95) choroid 4.7 3.4; 0.98) excellent. for vein 8.4 5.6, 0.90) 10.9 9.9, 0.9) moderate. MBRs disk had good both GHT+ group 3.8 0.97) GHT- 2.9 2.1; 0.95). Local assessment normal or showed COVs quadrant areas best temporal area (3.4%, 4.2%, respectively).LSFG-NAVI favorable evaluation patients, particularly