Tear osmolarity and dry eye symptoms in diabetics

• DOI: 10.2147/opth.s51514
• Publication Date: 2014-03-11T00:35:07Z
• Authors: Vatinee Bunya; Nicole Fuerst; Nicole Langelier; Mina Massaro-Gior...; Maxwell Pistilli; Carrie Burns; Serena Cardillo; Kalliopi Stasi
• Keywords: Osmotic concentration

To assess the relationship between tear osmolarity and dry eye symptoms in patients with diabetes.Fifty diabetes were enrolled. Demographic information past medical history recorded. Symptoms assessed using ocular surface disease index (OSDI). Tear of each was measured TearLab® Osmolarity System.The majority subjects female (76%), African American (56%), and/or had a diagnosis type 2 (82%). The mean ± standard deviation (SD) for age 54.6±13.4, maximum 304.6±12.7 mOsm/L. Men higher than women (mean error (SE) 311.8±4.0 mOsm/L versus 302.3±1.9 mOsm/L, P=0.02). Age, race, use artificial tears, years diabetes, hemoglobin A1c did not have statistically significant association osmolarity. Longer duration associated lower (less severe) OSDI scores (r=-0.35, P=0.01). Higher (r=-0.29, P=0.04).Approximately half diabetic our study elevated osmolarity, population also reported consistent disease. However, two slightly inversely related that those fewer symptoms. Subjects longer Therefore, health care providers should be aware who are most likely to disease, including long-standing may experience seek timely manner.