Quantification of heart, pericardium, and left ventricular myocardium movements during the cardiac cycle for thoracic tumor radiotherapy

• DOI: 10.2147/ott.s155680
• Publication Date: 2018-01-24T00:27:13Z
• Authors: Ying Tong; Yong Yin; Jie Lu; Tonghai Liu; Jinhu Chen; Pinjing Cheng; Guanzhong Gong
• Keywords: Cardiac cycle; Sphericity

The purpose of this study was to quantify variations in the heart, pericardium, and left ventricular myocardium (LVM) caused by cardiac movement using breath-hold technique.In study, electrocardiography-gated four-dimensional computed tomography (CT) images 22 patients were analyzed, which sorted into 20 phases (0-95%) according cycle. LVM contoured on each phase CT images. positions, volume, dice similarity coefficient (DSC) reference 0% phase, morphological parameters (max 3D diameter, roundness, spherical disproportion, sphericity, surface area) different presented as mean ± standard deviation.The values displacements along X, Y, Z axes respectively follows: 1.2 mm, 0.6 mm for heart; 0.5 0.4 0.8 pericardium; 1.0 4.1 1.9 LVM. maximum volume DSC 16.49%±3.85% 10.08%±2.14% 12.62%±3.94% 5.20%±1.54% 24.23%±11.35% 184.33%±128.61% differences between minimum heart pericardium not significantly (p>0.05) but (p<0.05).The volumetric similar those all smaller than This inconsistency indicates that special protection should be considered.