Quality of life in overweight (obese) and normal-weight women with polycystic ovary syndrome

• DOI: 10.2147/ppa.s119180
• Publication Date: 2017-03-02T22:29:22Z
• Authors: Annalisa Panico; Giovanni Messina; Gelsy Arianna Lupoli; Roberta Lupoli; Marianna Cacciapuoti; Fiorenzo Moscatelli; Teresa Esposito; Ines Villano; Anna Valenzano; Vincenzo Monda; Antonietta Messina; Francesco Precenzano; Giuseppe Cibelli; Marcellino Monda; Giovanni Lupoli
• Keywords: Pharmacology; 2. Zero hunger; Health-related quality-of-life; Normal-weight; Obesity; Polycystic ovary syndrome; Psychological disturbances; Medicine (General); Psychological disturbances; Health Policy; Medicine (miscellaneous); Health-related-quality-of-life; Toxicology and Pharmaceutics (miscellaneous); Health-related quality-of-life; 3. Good health; Normal-weight; 03 medical and health sciences; R5-920; 0302 clinical medicine; Patient Preference and Adherence; Psychological disturbance; Obesity; Polycystic ovary syndrome; Social Sciences (miscellaneous); Health-related quality-of-life; Normal-weight; Obesity; Polycystic ovary syndrome; Psychological disturbances; Medicine (miscellaneous); Social Sciences (miscellaneous); Pharmacology, Toxicology and Pharmaceutics (miscellaneous); Health Policy; Polycystic Ovary Syndrome; Original Research

Polycystic ovary syndrome (PCOS) is characterized by phenotypic heterogeneity and has a wide variety of consequences. Approximately half women with PCOS are overweight or obese, their obesity may be contributing factor to pathogenesis through different mechanisms. The aim this study was evaluate if alone affects the patients' quality life what extent contributes worsen disease.To impact on health-related quality-of-life (HRQoL), 100 Mediterranean (group A), 50 body mass index (BMI) >25 kg/m2 A1) BMI <25 A2), were recruited. They evaluated specific combination standardized psychometric questionnaires: Symptom Checklist-90 Revised, 36-Item Short-Form Health Survey, Ovary Syndrome Questionnaire. patients compared normal-weight healthy control group 40 subjects B). Another obese C) used make comparison (A1).Our results showed considerable worsening HRQoL in (A) controls (B). In addition, (A1) significant more marked reduction scores, suggesting lower life, (B) (A2).PCOS complex disease that determines deterioration HRQoL. innovative use these questionnaires study, particular questionnaire, highlighted negative effect It follows weight decrease associated spectrum improvement relative decrement psychological distress.