Higher Neutrophil-Percentage-to-Albumin Ratio Was Associated with Poor Outcome in Endovascular Thrombectomy Patients

thrombectomy. ischemic stroke npar Therapeutics. Pharmacology RM1-950 albumin Original Research
DOI: 10.2147/tcrm.s519263 Publication Date: 2025-04-26T04:20:15Z
ABSTRACT
The neutrophil percentage-to-albumin ratio (NPAR) is connected with all-cause mortality and stroke-related pneumonia. purpose of this study was to assess the diagnostic efficacy NPAR in predicting functional outcomes at 90 days after endovascular thrombectomy (EVT). We retrospective analyzed consecutive patients who underwent EVT Nanjing First Hospital from October 2019 June 2024. defined as percentage neutrophils divided by albumin levels. An unfavorable outcome indicated a modified Rankin Scale score 3-6 days. Multivariable logistic regression models were utilized investigate association between treatment. A total 713 (mean age, 70.5 ± 11.9 years; 430 males) finally enrolled for analysis. Among these, 357 (50.1%) exhibited Multivariate analysis that elevated levels admission independently associated poor (adjusted odds ratio: 6.921; 95% confidence interval, 4.216-11.363; P=0.001) ischemic stroke undergoing EVT. Furthermore, restricted cubic spline observed positive nonlinear (P linearity=0.001). This higher an increased risk treated EVT, suggesting could serve viable prognostic biomarker
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