Studying the effect of high-protein nutritional support on postoperative outcomes and during adjuvant chemotherapy in patients with primary gastric cancer

• DOI: 10.21518/ms2023-455
• Publication Date: 2024-01-19T06:34:36Z
• Authors: M. N. Khagazheeva; A. V. Snegovoy; A. M. Kelemetov; V. O. Tatyanin; N. M. Starostin
• Keywords: Tolerability; Mucositis; Regimen

Introduction . Malnutrition of cancer patients is a big problem today. This especially evident in with tumors the gastrointestinal tract, where frequency this condition reaches high values. has direct negative impact on tolerability treatment, long-term results and quality life category patients, so it important to identify and, if possible, correct it. Aim To evaluate effect protein nutritional support blood counts, prolongation intervals between chemotherapy courses, postoperative complications, progression-free expectancy OS gastric after surgical treatment during adjuvant chemotherapy. Materials methods The study included 106 who received followed by according XELOX regimen. were divided into 2 groups: first group, additional nutrition (Nutridrink Compact Protein) both before chemotherapy; second did not receive – control group. Results Median levels leukocytes, neutrophils platelets higher group 1. Surgical complications occurred significantly less frequently than same applies During lengthening courses statistically more often (without nutrition). 4-year overall survival was diet median PFS from amounted 55.6 months, 46.7 months. Conclusion presence an independent factor prognosis disease, since increases relapse-free patients.