Efficacy of Dietary Nucleotides (Nucleoforce™)on growth, haemato-immunological response and disease resistance in Pangasianodon hypophthalmus fish (Sauvage, 1878) in Egypt

• DOI: 10.21608/ejabf.2020.112821
• Publication Date: 2020-09-23T21:51:56Z
• Authors: Mai S. Yaseen; Mohamed Abdelaziz; Dalia A. Abdel-mo...; Elsayed Abd-Elhay; Islam M. Wassif; Mohamed Moustafa
• Keywords: 0401 agriculture, forestry, and fisheries; 04 agricultural and veterinary sciences

A feeding trial was performed to evaluate the efficacy of Dietary Nucleotides (Nucleoforce™) on Growth performance, haematological, biochemical, Immunological indices and disease resistance Pangasianodon hypophthalmus fish Pseudomonas aeruginosa. nucleotides were incorporated in diet at different concentrations; group I control, II 250 g/ ton III 500 for 8 weeks. At end trial, weight gain, specific growth rate (SGR) recorded. Results showed that there a significant increase groups received supplemented with comparison control group. Haematogram elevation RBCs count, HB value, WBCs, leukocytic count. Biochemically, High superoxide dismutase (SOD) activity, total protein globulin levels recorded fed 500g/t nucleotide (NT). Immunologically, Lymphocytic proliferation Nitric oxide concentration Serum lysozyme activity continuously increased 250g/t NT treatment along duration. 8th week, experimentally reared challenged intraperitoneally virulent strain aeruginosa (0.2 ml 3× 107 CFU) cumulative mortalities be lower compared In conclusion, supplementation can improve general health status P. via increasing minimizing stressful conditions.