THE ROLE OF LEPIDIUM SATIVUM SEED AND BOSWELLIA CARTERII POLAR EXTRACTS ‎IN AMELIORATING BLOOD GLUCOSE, LIPID PROFILE, IRON STATUS, IMMUNE ‎SYSTEM AND CARDIAC AND HEPATIC PATHOLOGY IN RAT MODEL OF DIABESITY

• DOI: 10.21608/ejchem.2021.103599.4805
• Publication Date: 2021-12-13T09:06:50Z
• Authors: Sahar Al-Okbi; Hagar Elbakry; Shaimaa Mohammed; Thanna Hamed; Asmaa Ramadan
• Keywords: Lepidium Sativum; Lipid Profile

Diabesity, a combined diabetes and obesity, is worldwide illness in the 21 century.The aim of present research was to study blood glucose, lipid profile, iron status, immune system cardiac hepatic pathology diabesity rat model potential protection by neutraceuticals.Dietary obesity were simultaneously induced rats as diabesity.Three nutraceuticals tested (Lepidium sativum seed ethanol water extracts Boswellia carterii extract).Biochemical analysis histopathological examination liver heart carried out.Phenolic flavonoidal contents determined Lepidium carterii.Results showed deficiency, dyslipidemia significantly elevated interleukin 6, glucose malondialdehyde, addition alteration histopathology control (DOC) group compared normal control.Treatment with different produced variable improvement DOC group.Lepidium higher phenolic than (p ≤ 0.05).Lepidium extract superior improving dyslipidemia, inflammation oxidative stress while most anti-diabetic.Lepidium best status.