Xanthine Oxidase Inhibitory Activity of Tetracera Indica

• DOI: 10.2174/2210289201304020093
• Publication Date: 2014-02-11T07:43:19Z
• Authors: Fauziah Abdullah; Nor Hadiani Ismail; Fadzureena Jamaludin; Siti Nur Aisyah M...
• Keywords: 01 natural sciences; 0104 chemical sciences

Preliminary screening study revealed that the methanolic extract of stem T. indica showed xanthine oxidase inhibitory activity in a concentration-dependent manner.EA fraction was selected to be further due its potential inhibit enzyme with IC 50 value 21.14 µg/ml which lower than MeOH extract, 42.02 µg/ml.Further separation and purification EA led isolation two known compounds.Those compounds were identified by analysis their spectroscopic data comparisons literature betulinic acid 5,7-dihydroxyl-8-methoxyflavone.