Identification of serodiscordant couples, their clinical and laboratory characteristics, and vulnerabilities of HIV transmission risk in Northeastern Brazil in the era of pre-exposure prophylaxis (PrEP)

• DOI: 10.21876/rcshci.v10i2.931
• Publication Date: 2020-06-09T18:37:34Z
• Authors: Maíra Gomes Monteiro; Adriana Farrant Braz; Kledoaldo Lima; Heloísa Ramos Lac...
• Keywords: Serodiscordant; Pre-exposure prophylaxis; Hepatitis B

Objectives: To evaluate the frequency of HIV serodiscordants couples and their seronegative partners who were candidates for pre-exposure prophylaxis (PrPE), knowledge about behavioural measures to reduce virus transmission. Methods: The research was performed in Northeastern Brazil, from February 2016 March 2017. Ninety HIV-positive individuals (Index) HIV-serodiscordant (n = 17) submitted epidemiological, clinical, laboratory questionnaires, rapid tests syphilis, hepatitis B C. Results: High frequencies HIV-syphilis (34.4%) HIV-HBV (3.3%) coinfection detected individuals. Three new cases partners. Most participants both groups (85.6%, Index; 94.1%, Partners) had an excellent degree regarding transmission, although nine with a high risk infection identified (53%). co-infection 10% them did not use antiretroviral by personal option. Conclusions: Adoption PrEP other preventive prevent transmission should be studied evaluated.