A Wearable Technology Delivering a Web-Based Diabetes Prevention Program to People at High Risk of Type 2 Diabetes: Randomized Controlled Trial

• DOI: 10.2196/15448
• Publication Date: 2020-02-29T20:00:25Z
• Authors: Emily Staite; Adam Bayley; Ebaa Al-Ozairi; Kurtis Stewart; David Hopkins; Jennifer Rundle; Neel Basudev; Zahra Mohamedali; Khalida Ismail
• Keywords: Prediabetes; Motivational Interviewing; mHealth

Intensive lifestyle interventions are effective in reducing the risk of type 2 diabetes, but implementation learnings from landmark studies is expensive and time consuming. The availability digital increasing, evidence their effectiveness limited.This randomized controlled trial (RCT) aimed to test feasibility a web-based diabetes prevention program (DPP) with step-dependent feedback messages versus standard DPP people prediabetes.We employed two-arm, parallel, single-blind RCT for at high developing diabetes. Patients hemoglobin A1c (HbA1c) level 39-47 mmol/mol were recruited 21 general practices London. intervention integrated smartphone app delivering course SMS texts incorporating motivational interviewing techniques delivered via wearable device over 12 months. control group received technology access DDP not texts. As this was study, primary aim estimate potential sample size different stages including target study population proportion participants who consented, randomized, completed follow-up. We also measured main outcomes full-scale RCT, namely, change weight physical activity 6- 12-month follow-ups, secondary outcomes, changes HbA1c level, blood pressure, waist circumference, waist-to-hip ratio, lipid levels.We enrolled 200 participants: 98 102 group. follow-up rate higher (87/102, 85.3%) than (69/98, 70%) There no treatment effect on 6 months (mean difference 0.15; 95% CI -0.93 1.23) or 0.07 kg; -1.29 1.44) levels -382.90 steps; -860.65 94.85) 92.64 -380.92 566.20). did observe 6-month For group, mean 92.33 (SD 15.67) kg baseline, 91.34 16.04) months, 89.41 14.93) 92.59 17.43) 91.71 16.48) 91.10 15.82) In 7308.40 4911.93) steps 5008.76 2733.22) 4814.66 3419.65) 7599.28 3881.04) 6148.83 3433.77) 5006.30 3681.1) months.This demonstrates that it feasible successfully recruit retain patients an DPP.ClinicalTrials.gov NCT02919397; http://clinicaltrials.gov/ct2/show/NCT02919397.