Electronic Versus Paper-Based Assessment of Health-Related Quality of Life Specific to HIV Disease: Reliability Study of the PROQOL-HIV Questionnaire

• DOI: 10.2196/jmir.3330
• Publication Date: 2014-04-25T16:17:55Z
• Authors: Martin Duracinsky; Christophe Lalanne; Cécile Goujard; Susan Herrmann; Christian Cheung-...; Jean-Paul Brosseau; Yannick Schwartz; Olivier Chassany
• Keywords: Adult; Male; Paper; Psychometrics; Computer applications to medicine. Medical informatics; R858-859.7; HIV Infections; 02 engineering and technology; 310; User-Computer Interface; 03 medical and health sciences; 0302 clinical medicine; Surveys and Questionnaires; Outcome Assessment, Health Care; 0202 electrical engineering, electronic engineering, information engineering; Electronic Health Records; Humans; Original Paper; Analysis of Variance; Internet; Cross-Over Studies; Computers; Reproducibility of Results; Middle Aged; 3. Good health; Quality of Life; Female; Self Report; Public aspects of medicine; RA1-1270

Background: Electronic patient-reported outcomes (PRO) provide quick and usually reliable assessments of patients' health-related quality life (HRQL). Objective: An electronic version the Patient-Reported Outcomes Quality Life-human immunodeficiency virus (PROQOL-HIV) questionnaire was developed, its face validity reliability were assessed using standard psychometric methods. Methods: A sample 80 French outpatients (66% male, 52/79; mean age 46.7 years, SD 10.9) recruited. Paper-based questionnaires completed in a randomized crossover design (2-7 day interval). Biomedical data collected. Questionnaire order effects tested on full-scale scores 2-way ANOVA with patients as random effects. Test-retest evaluated Pearson intraclass correlation coefficients (ICC, 95% confidence interval) for each dimension. Usability testing carried out from survey reports, specifically, general satisfaction, ease completion, clarity user interface, motivation to participate follow-up PROQOL-HIV assessments. Results: administration (N=59 complete cases) not significant at 5% level, no interaction found between these 2 factors (P=.94). Reliability indexes acceptable, correlations greater than .7 ICCs ranging .708 .939; statistically different two versions. total 63 (79%) reports available, 55% (30/55) reported being satisfied interested assessment their HRQL clinical follow-up. Individual ratings interface (85%-100% positive responses) confirmed usability. Conclusions: The introduces minor modifications original paper-based version, following International Society Pharmacoeconomics Research (ISPOR) ePRO Task Force guidelines, shows good validity. Patients can computerized paper or versions share comparable accuracy interpretation.