A Newly Designed Mobile-Based Computerized Cognitive Addiction Therapy App for the Improvement of Cognition Impairments and Risk Decision Making in Methamphetamine Use Disorder: Randomized Controlled Trial (Preprint)

• DOI: 10.2196/preprints.10292
• Publication Date: 2018-03-03T23:22:18Z
• Authors: Youwei Zhu; Haifeng Jiang; Hang Su; Na Zhong; Runji Li; Xiaotong Li; Tianzhen Chen; Haoye Tan; Jiang Du; Ding Xu; Huan Yan; Dawen Xu; Min Zhao
• Keywords: Stroop effect

<sec> <title>BACKGROUND</title> Cognitive rehabilitation therapy has been found to improve cognitive deficits and impulse control problems in methamphetamine use disorder (MUD). However, there is limited research regarding this therapy’s feasibility when using mobile-based health technologies supporting recovery from MUD China. </sec> <title>OBJECTIVE</title> The main aim of study was test whether 4 weeks a newly designed computerized addiction (CCAT) app can impairments, eliminate drug-related attention bias, attenuate risk decision-making behaviors participants with MUD. <title>METHODS</title> Forty were assigned randomly either the CCAT group (n=20), who received plus regular detoxification treatment as usual, or only drug centers Shanghai. by combine use-related picture stimuli training improving function eliminating bias. CogState Battery, Delay Discounting Task (DDT), Iowa Gambling (IGT), Balloon Analog Risk (BART) administered face-to-face all before after interventions. <title>RESULTS</title> male patients recruited. mean age 32.70 (SD 5.27) years 35.05 8.02) group. Compared group, improved working memory (P=.01). Group×time interactions observed among DDT, IGT, BART tasks, rates discounting delayed rewards, scores (P&lt;.001) being reduced those CCAT, whereas no changes <title>CONCLUSIONS</title> help impairment impulsive Further needed understand underlying brain mechanisms therapy. <title>CLINICALTRIAL</title> ClinicalTrials.gov NCT03318081; https://clinicaltrials.gov/ct2/show/NCT03318081 (Archived WebCite at https://clinicaltrials.gov/ct2/show/NCT03318081)