Early Postpartum Glucose Intolerance, Metabolic Syndrome and Gestational Diabetes Mellitus Determinants after Assisted Conception: A Prospective Cohort Study.

• DOI: 10.22074/ijfs.2021.522566.1070
• Publication Date: 2022-08-21
• Authors: Azam Kouhkan; Roya Hosseini; Hamid Reza Baradaran; Arezoo Arabipoor; Rezvan Cheraghi; Ashraf Moini; Farideh Malekzadeh; Mohammad E. Khamseh

This study aimed to determine the prevalence of postpartum metabolic syndrome (MetS), glucose intolerance,<br />and determinants, 6-12 weeks in women with assisted reproduction technology conception<br />gestational diabetes mellitus diagnosis (ART-GDM) compared spontaneous conception and GDM<br />diagnosis (SC-GDM).<br />Materials Methods: In this prospective cohort study, two groups consisting 62 ART-GDM 64 SC-GDM<br />singleton pregnant were followed after delivery for MetS. Fasting glucose, 75-g 2-h<br />OGTT, lipid profile assessed. Waist hip circumference, systolic diastolic blood pressures (BP)<br />were measured at postpartum. Clinical, paraclinical, obstetric data recorded from registry offices. The prevalence<br />of MetS intolerance determined. Predictors evaluated<br />by logistic regression.<br />Results: was 20.8% 10.9% SC-GDM (P=0.123).<br />Mean BMI BP significantly higher group (P=0.016 P=0.027<br />respectively). Adverse pregnancy outcomes group. Postpartum glucose<br />intolerance did not vary between groups. Family history a predictive factor<br />for delivery.<br />Conclusion: Early significantly;<br />however, body mass index (BMI) group.<br />Lifestyle modification programs long-term health care ART GDM can be recommended.<br />Further studies larger sample size longer follow-up are necessary verify our findings.