Improving Fertility in Non-obstructive Azoospermia: Results from an Autologous Bone Mar-row-Derived Mesenchymal Stromal/Stem Cell Phase I Clinical Trial.

• DOI: 10.22074/ijfs.2023.2005045.1480
• Publication Date: 2024-07-13
• Authors: Rano Zhankina; Ulanbek Zhanbyrbe...; Manarbek Askarov; Afshin Zare; Nazanin Jafari; Dana Saipiyeva; Ravil Sherkhanov; Daniyar Akhmetov; Alireza Hashemi; Mojtaba Farjam; Nader Tanideh; Behrouz Aflatoonian; Nadiar M. Mussin; Asset Askerovich ...; Yerlan Sultangereyev; Hanieh Baneshi; Reza Shirazi; Mahdi Mahdipour; Shabnam Bakhshali...; Farhad Rahmanifar; Amin Tamadon
• Keywords: Obstructive azoospermia

In this phase I clinical trial, our primary objective was to develop an innovative therapeutic approach utilizing autologous bone marrow-derived mesenchymal stromal/stem cells (BM-MSCs) for the treatment of nonobstructive azoospermia (NOA). Additionally, we aimed assess feasibility and safety approach.