Characterization of Focal Bone Lesions in the Axial Skeleton: Performance of Planar Bone Scintigraphy Compared with SPECT and SPECT Fused with CT

• DOI: 10.2214/ajr.06.1215
• Publication Date: 2007-04-20T18:50:26Z
• Authors: Klaus Strobel; Cyrill Burger; Burkhardt Seifert; Daniela B. Husarik; Jan D. Soyka; Thomas F. Hany
• Keywords: Bone scintigraphy; Axial skeleton; Skeleton (computer programming); Bone imaging; Characterization

The purpose of this study was to evaluate the diagnostic performance planar 99mTc methylene diphosphonate bone scintigraphy compared with SPECT and fused CT in patients focal lesions axial skeleton.Thirty-seven 42 skeleton were included prospective study. All underwent scintigraphy, through lesions, SPECT-guided CT. images then digitally. three types evaluated separately from one another by two experienced reviewers working consensus. Visibility performance, certainty diagnosis evaluated. Performance for specific diagnoses also Histologic, MRI, clinical follow-up findings used as reference standard.Visibility significantly better than (p < 0.0001). Sensitivity specificity differentiation benign malignant 82% 94% 91% SPECT, 100% Differences between methods differentiating did not reach statistical significance. Certainty higher = 0.004) 0.004). A made 64% cases, 86%, all cases.Planar may suffice skeleton, but increases is best tool making a diagnosis.