Estimated Radiation Dose Reduction Using Adaptive Statistical Iterative Reconstruction in Coronary CT Angiography: The ERASIR Study

• DOI: 10.2214/ajr.10.4288
• Publication Date: 2010-08-20T18:35:19Z
• Authors: Jonathon Leipsic; Troy M. LaBounty; Brett Heilbron; James K. Min; G. B. John Mancini; Fay Y. Lin; Carolyn Taylor; Allison Dunning; James P. Earls
• Keywords: Male; Chi-Square Distribution; Models, Statistical; Contrast Media; Coronary Disease; Middle Aged; Coronary Angiography; Radiation Dosage; Statistics, Nonparametric; Radiation Protection; Triiodobenzoic Acids; Linear Models; Humans; Radiographic Image Interpretation, Computer-Assisted; Female; Prospective Studies; Tomography, X-Ray Computed; Software

The objective of our study was to assess the impact Adaptive Statistical Iterative Reconstruction (ASIR) on radiation dose and quality for coronary CT angiography (CTA).We prospectively evaluated 574 consecutive patients undergoing CTA at three centers. Comparisons were performed between groups initially using filtered back projection (FBP) (n = 331) subsequently ASIR 243) with regard patient scan characteristics, dose, diagnostic quality.There no difference in use prospective gating, tube voltage, or length. examinations had a lower median current than those obtained FBP (median [interquartile range], 450 mA [350-600] vs 650 [531-750], respectively; p < 0.001). There 44% reduction cohorts (4.1 mSv [2.3-5.2] 2.3 [1.9-3.5]; After adjustment settings, associated 27% compared (95% CI, 21-32%; Despite reduced current, not adjusted signal, noise, signal-to-noise ratio (p significant). No differences existed interpretability per artery (98.5% 99.3%, 0.12) (96.1% 97.1%, 0.65). CONCLUSION. enabled comparison FBP, preserved interpretability, large multicenter cohort. represents new technique reduce studies.