Hypervascular Hepatocellular Carcinoma 1 cm or Smaller in Patients With Chronic Liver Disease: Characterization With Gadoxetic Acid–Enhanced MRI That Includes Diffusion-Weighted Imaging

• DOI: 10.2214/ajr.10.4394
• Publication Date: 2011-05-23T18:35:44Z
• Authors: Ji-Eun Kim; Seong Hyun Kim; Soon Jin Lee; Hyunchul Rhim
• Keywords: Gadoxetic acid; Chronic liver disease; Univariate analysis

The purpose of this study was to determine the finding most predictive for characterizing hypervascular hepatocellular carcinoma (HCC) measuring 1 cm or less at gadoxetic acid-enhanced MRI that includes diffusion-weighted images.In retrospective study, between May 2008 and June 2009, 66 patients with 108 HCCs smaller underwent 3-T included images. diagnosis HCC determined by surgical resection in 32 cases, percutaneous biopsy three interval growth larger than on follow-up images accordance American Association Study Liver Diseases guidelines 73 cases. findings 33 benign lesions a control group were analyzed two radiologists consensus. They based their assessments presence absence following five findings: hyperintensity T2-weighted images, low b values, washout pattern, capsular enhancement, hypointensity hepatobiliary phase compared use univariate multivariate analyses.No enhancement found. Fifty-seven (52.8%) had four findings, 36 (33.3%) three, nine (8.3%) six (5.6%) one finding. Univariate analysis showed significant differences groups respect (p < 0.0001). Multivariate 0.0001) = 0.0081) statistically predicting HCC.Hyperintensity both T2- is helpful diameter.