Combined Chemical Shift Imaging With Early Dynamic Serial Gadolinium-Enhanced MRI in the Characterization of Adrenal Lesions

• DOI: 10.2214/ajr.13.11731
• Publication Date: 2014-06-21T01:05:53Z
• Authors: Karina Rodacki; Miguel Ramalho; Brian M. Dale; Sofia Battisti; Rafael O. P. de C...; Antonello Giardino; Richard C. Semelka
• Keywords: Characterization

The purpose of this study was to retrospectively evaluate early dynamic serial gadolinium-enhanced and chemical-shift imaging (CSI) MRI distinguish benign from malignant adrenal tumors.Between July 2007 December 2011, 205 patients with 239 lesions (177 adenomas, 54 metastases, 5 pheochromocytomas, 3 cortical carcinomas) underwent CSI. CSI assessed qualitatively by calculating the index, enhancement patterns were evaluated quantitatively. Statistical analyses performed.Most adenomas exhibited either an arterial blush or homogeneous enhancement, whereas most metastases showed peripheral heterogeneous enhancement. Visualization higher on venous phases enabled differentiation in cases. Moderate high signal intensity drop seen 95.4% 14.8% metastases. In level drop, 87 88 a capillary adenomas. Early alone significant (p < 0.0001) indicator nonadenoma (area under curve [AUC], 0.912) optimal sensitivity 81% specificity 93% for differentiating nonadenomas. Combined analysis (CSI imaging) also 0.0001 p=0.0014, respectively) diagnosing nonadenomas (AUC, 0.983) 94% 98%.Early aids characterization tumors, especially that are categorized as indeterminate basis