Concurrent Computer-Aided Detection Improves Reading Time of Digital Breast Tomosynthesis and Maintains Interpretation Performance in a Multireader Multicase Study

• DOI: 10.2214/ajr.17.18185
• Publication Date: 2017-10-24T18:07:31Z
• Authors: Richard A. Benedikt; Justin E. Boatsman; Cynthia A. Swann; Aaron D. Kirkpatrick; Alicia Y. Toledano
• Keywords: Tomosynthesis; Digital Breast Tomosynthesis

Digital breast tomosynthesis (DBT) is more accurate than full-field digital mammography alone but requires a longer reading time. A radiologist reader study evaluated the use of concurrent computer-aided detection (CAD) to shorten time while maintaining interpretation performance.A CAD system was developed detect suspicious soft-tissue densities in DBT planes. Abnormalities are extracted from plane which they detected and blended into corresponding synthetic image. The used an enriched sample 240 cases with 68 malignancies 61 patients. Twenty radiologists retrospectively reviewed all multireader multicase crossover design compare performance without CAD. also evaluated.Reading improved by 29.2% (95% CI, 21.1-36.5%; p < 0.01). Reader performance, measured ROC AUC, noninferior (p mean AUC increased 0.841 0.850 -0.012 0.030). Mean sensitivity 0.847 0.871 (difference 95% -0.005 0.055), showing 0.033 increase for -0.002 0.068). specificity decreased 0.527 0.509 -0.041 0.005), recall rate noncancers slightly 0.474 0.492 -0.006 0.041).Concurrent resulted faster time, performance.