Managing Chorea in Huntington’s Disease

• DOI: 10.2217/nmt.11.40
• Publication Date: 2012-03-12T14:18:39Z
• Authors: Okeanis Vaou; Samuel Frank
• Keywords: Tetrabenazine; Movement Disorders

SUMMARY Huntington's disease (HD) is an inherited, neurodegenerative disorder characterized by progressive motor dysfunction, abnormal involuntary movements, emotional disturbances and cognitive decline. There currently no treatment to modify the progression of HD. Until modifying agents are established, symptomatic remains cornerstone management. Treating chorea other symptoms may improve quality life sufferers. Multiple interventions have been studied for chorea, but tetrabenazine only US FDA-approved drug indicated associated with In this article, medications available will be summarized investigational management also briefly reviewed. Although constitutes part HD, movements can disabling, injurious or bothersome.