Low in vitro third-body wear on total hip prostheses induced by calcium sulphate used for local antibiotic therapy

• DOI: 10.22203/ecm.v028a17
• Publication Date: 2016-11-16T16:16:16Z
• Authors: R Heuberger; P Wahl; J Krieg; E Gautier
• Keywords: Antibiotic Therapy

In case of implant associated infection, preservation is with high failure rates.Therefore, a removal or exchange the most often mandatory for treatment success.Alternatively, under certain conditions, local antibiotic delivery can be applied -preserving implant, using example calcium sulphate as resorbable carrier.In this work, third-body wear on total hip prostheses caused by particles was tested in simulator.Inlays made ultra-high-molecular-weight polyethylene (UHMWPE) and cross-linked (XLPE) against 28 mm CoCrMo heads 36 alumina pairings were triplicate, both without test liquid.Neither articulations nor affected since relatively soft material.The inlays showed 39-89 % higher during exposure compared to references, but returned normal when no more added.Thus, might used carrier even presence fearing excessive wear.