Geographical contrasts of Y-chromosomal haplogroups from wild and domestic goats reveal ancient migrations and recent introgressions

• DOI: 10.22541/au.164744277.74322182/v1
• Publication Date: 2022-03-16T14:59:44Z
• Authors: Vargoats Consortium; Isaäc Nijman; Benjamin Rosen; Philippe Bardou; Thomas Faraut; Tristan Cumer; Kevin Daly; Zhuqing Zheng; Yudong Cai; Hojjat Asadollahpour; Bengi Cinar-Kul; Wei-Yi Zhang; guangxin e; A Ayin; Hayley Baird; Meirat Bakhtin; Valentin Balteanu; Diana Barfield; Beate Berger; Thor Blichfeldt; Geert Boink; Sri Rachma Bugiwati; Zexi Cai; Sean Carolan; Emily Clark; Vladka Cubrić Curik; Muhammad Dagong; Tashi Dorji; Louise Drew; Jiazhong Guo; Jón Hallsson; Simon Horvat; Juha Kantanen; Fuki Kawaguchi; Polat Kazymbet; Negar khayatzadeh; Namshin Kim; Manoj Kumar Shah; Yuying Liao; Amparo Martinez; Joseph Masangkay; Maho Masaoka; Raffaele Mazza; John McEwan; Marco Milanesi; Md Omar Faruque; Yuto Nomura; Nadjet-Amina Ouch...; Filipe Pereira; Goutam Sahana; Mazdak Salavati; Shinji Sasazaki; Anne DA SILVA; Mojca Simčič; Johann Soelkner; Alison Sutherland; Johannes Tigchelaar; Hongping Zhang; Econogene Consortium; Paolo Ajmone Marsan; Daniel Bradley; Licia Colli; Cord Drögemüller; Yu Jiang; chuzhao Lei; H Mannen; Francois Pompanon; GWENOLA TOSSER-KLOPP; Johannes A. Lenstra
• Keywords: Haplogroup; Introgression; Gene pool

By their paternal transmission, Y-chromosomal haplotypes are sensitive markers of population history and male-mediated introgression. Previous studies identified biallelic single-nucleotide variants in the SRY, ZFY, DDX3Y genes, which domestic goats four major Y1A, Y1B, Y2A Y2B with a marked geographic partitioning. Here, we analyze whole-genome sequences 386 from 75 modern breeds 7 wild goat species that were generated by VarGoats genome project. Phylogenetic analyses indicated haplogroups corresponding to Y2B, respectively, whereas Y1A is split into Y1AA Y1AB. All five detected 26 ancient DNA samples southeast Europe or Asia. Haplotypes present-day bezoars not shared attached deep nodes trees networks. Haplogroup distributions for 180 indicate bottlenecks expansions during migrations northern Europe, eastern southern Asia Africa south Sahara. In addition, sharing indicates introgressions, most notably an early gene flow Asian Madagascar crossbreeding 19th century resulted popular Boer Anglo-Nubian breeds. More recent introgressions those European native Korean Uganda, Kenya, Tanzania, Malawi Zimbabwe. This study illustrates power reconstructing wide range.