Effect of Cobalt-60 Irradiation on the Infectivity of Paragonimus westermani Metacercariae

• DOI: 10.2307/3283319
• Publication Date: 2006-05-06T09:44:06Z
• Authors: Chang-cun Song; Yun-fen Duan; Gan-cheng Shou; Hua Zhu
• Keywords: Paragonimus westermani; Paragonimus; Infectivity

A study was made to observe the effect of cobalt-60 irradiation on viability Paragonimus westermani metacercariae in Sinopotamon chekiangense crabs. The crabs were collected mountain regions Zhejiang Province China which paragonimiasis is endemic. Adult cats and albino mice infected with irradiated at different doses. Dissection host animals conducted 90 or 30 days, respectively, after infection for recovery lung flukes. Anti-metacercariae antibody measured by enzyme-linked immunosorbent assay (ELISA). Results showed that unable grow into adult worms exposure gamma a dose 0.10 kGray. However, small number exposed 2.0 kGray excysted survived 1 mouse days. No worm recovered from when 2.5 Seropositive results ELISA obtained doses ranging 3.5