Biologic Effects of Microwave Exposure: I. Threshold Conditions for the Induction of the Increase in Complement Receptor Positive (CR + ) Mouse Spleen Cells Following Exposure to 2450-MHz Microwaves

• DOI: 10.2307/3575264
• Publication Date: 2006-11-16T21:32:55Z
• Authors: Kazimierz Sulek; Charles J. Schlagel; Wieslaw Wiktor-Je...; Henry S. Ho; William M. Leach; Aftab Ahmed; James N. Woody
• Keywords: 0301 basic medicine; Time Factors; Body Weight; Complement C3; Radiation Dosage; Body Temperature; Receptors, Complement; Mice; 03 medical and health sciences; Animals; Lymphocytes; Microwaves; Spleen

A significant increase in the percentage of spleen cells bearing receptor for third component complement (CR/sup +/) was induced mice following a single exposure to 2450-MHz microwave radiation an environmentally controlled waveguide facility (24/sup 0/C, 50% relative humidity, 38 liters/min airflow). This icrease composed surface immunoglobulin-positive, Thy-1-negative-cells, and observed by 3 days exposure; it persisted 5 6 returned baseline levels 9 10 after exposure. No secondary increases were observed. The threshold level absorbed energy required trigger inductive events determined using two experimental protocols: (a) varying time constant forward power (0.6 W), or (b) maintaining while (0.1 0.78 W). It that minimum 15-min W; 11.8 W/kg; 10.6 J/g) 30-min (0.3 5.0 9.07 on Day 3, which peaked 6. Once this critical (9.07 attained, response maximal. effect absorption multiplemore » subthreshold quantities cumulative, provided exposures occurred within 1 h one another. When 24 elapsed between CR/sup +/ not observed.« less