Acetazolamide Loading Matas Test as a Preoperative Test for Internal Carotid Cavernous Giant Aneurysms

• DOI: 10.2335/scs1987.20.6_437
• Publication Date: 2014-11-06T23:50:56Z
• Authors: Tetsuo YAMASHITA; Shiro KASHIWAGI; Masaaki HAYASHI; Teiichi TAKASAGO; Yuki EGUCHI; Shigenari KIN; Manabu URAKAWA; Yujiro SHIROYAMA; Haruhide ITO
• Keywords: Acetazolamide

In the present study we evaluated cerebrovascular reserve capacity (CRC) during temporal occlusion of internal carotid artery (Matas test) as a preoperative test in selection candidates for permanent ligation from among patients with cavernous giant aneurysms. Cerebral blood flow (CBF) rest (resting CBF), Matas (Matas-CBF), and after administration 1g acetazolamide (acetazolamide-Matas-CBF) were measured using stable xenon-enhanced CT CBF technique (Xe-CT). This procedure was named “Acetazolamide loading test.”The CRC (Matas-CRC) calculated difference between Matas-CBF acetazolamide-Matas-CBF.In case 51-year-old male left aneurysm, showed resting CBF, Matas-CBF, Matas-CRC within normal limits. The surgically trapped without complication.Among aneurysms, those the“Acetazolamide test”were found to be good ligation.