Validity of a Single-Factor Model Underlying the Metabolic Syndrome in Children

• DOI: 10.2337/dc09-2049
• Publication Date: 2010-03-19T00:46:55Z
• Authors: Vicente Martínez-...; Montserrat Solera...; Fernando Salcedo ...; Sandra Serrano Ma...; Ricardo Franquelo...; Mairena Sánchez L...; Pablo Moya Martínez; Fernando Rodrígue...
• Keywords: Male; Metabolic Syndrome; Adolescent; Cholesterol, HDL; Blood Pressure; 03 medical and health sciences; 0302 clinical medicine; Humans; Insulin; Female; Waist Circumference; Child; Factor Analysis, Statistical; Triglycerides; Original Research

OBJECTIVE We used confirmatory factor analysis to test whether a single might explain the clustering of metabolic syndrome (MS) components in children. RESEARCH DESIGN AND METHODS studied 1,020 children aged 10–13 years from 20 schools Cuenca, Spain. The single-factor model included: waist circumference (WC), fasting insulin, triglyceride HDL cholesterol ratio (Triglyl/HDL-C), and mean arterial pressure (MAP). standardized scores four variables were develop continuous MS index. RESULTS Factor loadings 0.67 for WC, 0.68 0.57 Triglyl/HDL-C, 0.37 MAP. also showed good fit data. As compared with Adult Treatment Panel III criteria, index strong validity diagnosis (area under receiver operating characteristic curve = 0.98, 95% CI 0.96–0.99). CONCLUSIONS A underlying has acceptable represent