Impact of Restricted Maternal Weight Gain on Fetal Growth and Perinatal Morbidity in Obese Women With Type 2 Diabetes

• DOI: 10.2337/dc12-1232
• Publication Date: 2012-12-18T05:45:56Z
• Authors: Björg Ásbjörnsdóttir; Signe S. Rasmussen; Louise Kelstrup; Peter Damm; Elisabeth R. Math...
• Keywords: Adult; 2. Zero hunger; Middle Aged; Weight Gain; 3. Good health; Fetal Development; Young Adult; 03 medical and health sciences; 0302 clinical medicine; Diabetes Mellitus, Type 2; Pregnancy; Birth Weight; Humans; Female; Obesity; Original Research; Retrospective Studies

OBJECTIVE Since January 2008, obese women with type 2 diabetes were advised to gain 0–5 kg during pregnancy. The aim this study was evaluate fetal growth and perinatal morbidity in relation gestational weight these women. RESEARCH DESIGN AND METHODS A retrospective cohort comprised the records of 58 singleton pregnancies (BMI ≥30 kg/m2) giving birth between 2008 2011. Birth evaluated by SD z score adjust for age sex. RESULTS Seventeen (29%) gained ≤5 kg, remaining 41 >5 kg. median (range) gains 3.7 (−4.7 5 kg) 12.1 (5.5–25.5 kg), respectively. Prepregnancy BMI 33.5 kg/m2 (30–53 vs. 36.8 (30–48 kg/m2), P = 0.037, HbA1c 6.7% at first visit both groups decreased 5.7 6.0%, 0.620, late pregnancy, Gestational associated lower (P 0.008), rates large-for-gestational-age (LGA) infants (12 39%, 0.041), delivery closer term (268 262 days, 0.039), less (35 71%, 0.024) compared maternal CONCLUSIONS In pilot diabetes, a more proportionate morbidity.