Severity of Neuropathy Is Associated With Long-term Spinal Cord Stimulation Outcome in Painful Diabetic Peripheral Neuropathy: Five-Year Follow-up of a Prospective Two-Center Clinical Trial

• DOI: 10.2337/dc17-0983
• Publication Date: 2017-11-07T01:20:10Z
• Authors: Maarten van Beek; José W. Geurts; Rachel Slangen; Nicolaas C. Schaper; Catharina G. Faber; Elbert A. Joosten; Carmen D. Dirksen; Robert T. van Dongen; Sander M.J. van K...; Maarten van Kleef
• Keywords: Single Center; Diabetic Neuropathy

OBJECTIVE Evidence from prospective studies for long-term treatment efficacy of spinal cord stimulation (SCS) in painful diabetic peripheral neuropathy (PDPN) is not available. We report data on the effect SCS pain ratings, success and failure, complications during a 5-year follow-up patients with PDPN. RESEARCH DESIGN AND METHODS Patients PDPN (n = 48) were included this multicenter study. The Michigan Diabetic Neuropathy Score (MDNS) was used to assess severity neuropathy. Numerical rating scale (NRS) score pain, Patient’s Global Impression Change (PGIC), (50% reduction NRS or significant PGIC) 5 years evaluated. Complications reported, associations between baseline characteristics trial failure investigated by using survival analyses. RESULTS Treatment observed 55% after years. Median duration 60 months (minimum 1 month, maximum months), 80% permanent implant still their device Higher MDNS associated (hazard ratio 3.9 [95% CI 1.3–11.6]; P 0.014). CONCLUSIONS successful reducing chronic symptoms lower extremities up initiation treatment. Furthermore, use Moreover, higher chance follow-up.