The Effect of a Novel Low-Volume Aerobic Exercise Intervention on Liver Fat in Type 2 Diabetes: A Randomized Controlled Trial

• DOI: 10.2337/dc19-2523
• Publication Date: 2020-07-31T02:36:42Z
• Authors: Angelo Sabag; Kimberley L. Way; Rachelle N. Sultana; Shelley E. Keating; James A. Gerofi; Vivienne H. Chuter; Nuala M. Byrne; Michael K. Baker; Jacob George; Ian D. Caterson; Stephen M. Twigg; Nathan A. Johnson
• Keywords: Aerobic Exercise

The aim of this study was to examine the effect a novel low-volume high-intensity interval training (HIIT), moderate-intensity continuous (MICT), or placebo (PLA) intervention on liver fat, glycemia, and cardiorespiratory fitness using randomized placebo-controlled design.Thirty-five inactive adults (age 54.6 ± 1.4 years, 54% male; BMI 35.9 0.9 kg/m2) with obesity type 2 diabetes were 12 weeks supervised MICT (n = 12) at 60% VO2peak for 45 min, 3 days/week; HIIT 90% 4 PLA 11). Liver fat percentage quantified through proton MRS.Liver reduced in (-0.9 0.7%) (-1.7 1.1%) but increased (1.2 0.5%) (P 0.046). HbA1c improved (-0.3 0.3%) not (0.5 0.2%) 0.014). Cardiorespiratory (2.3 1.2 mL/kg/min) (1.1 0.5 (-1.5 0.006).MICT approach involving min weekly aerobic exercise may improve people absence weight loss. Further studies are required elucidate relationship between exercise-induced reductions improvements glycemia.