Analgesia Nociception Index-guided intraoperative fentanyl consumption and postoperative analgesia in patients receiving scalp block versus incision-site infiltration for craniotomy

• DOI: 10.23736/s0375-9393.18.12837-9
• Publication Date: 2018-12-04T11:29:30Z
• Authors: Kaushic A. Theerth; Kamath Sriganesh; K. Madhusudan Reddy; Dhritiman Chakrab...; Ganne S. Umamahes...
• Keywords: Interquartile range; FLACC scale

Scalp block or local anesthetic infiltration for craniotomy blunts hemodynamic response to noxious stimuli, reduces opioid requirement and decreases postoperative pain. Analgesia Nociception Index (ANI) provides objective information about the magnitude of pain (rated from 0 100 with indicating extreme nociception absence nociception) adequacy intra-operative analgesia. This study compared fentanyl consumption guided by ANI in patients who receive scalp those incision-site craniotomy.Sixty adult undergoing elective supra-tentorial tumor surgery were randomly allocated after induction anesthesia. Throughout period, received 0.5 µg/kg/h was continuously monitored. Fentanyl 1 µg/kg bolus administered when decreased <50. Intraoperative using unpaired t-test. Correlation between numerical rating scale (NRS) score done Spearman's rho.The (µg/kg/h) less (median [interquartile range]; 1.04 [0.92-1.34] vs. 1.34 [1.18-1.59], P=0.001). Postoperative scores similar [median (interquartile range); 1.5 (0-4) 3 (0-4), P=0.840]. No correlation observed NRS Score (correlation coefficient = 0.072; P=0.617).ANI-guided analgesic administration during demonstrated lower receiving as infiltration. seen ANI.