Acute kidney injury and mortality in coronavirus disease 2019: results from a cohort study of 1,280 patients

• DOI: 10.23876/j.krcp.20.128
• Publication Date: 2021-06-02T07:30:31Z
• Authors: Natalia Chebotareva; Svetlana Berns; Angelina Berns; Tatyana Androsova; Marina Lebedeva; Sergey Moiseev
• Keywords: Coronavirus; 2019-20 coronavirus outbreak

Background The development of acute kidney injury (AKI) in patients with coronavirus disease 2019 (COVID-19) is associated a high risk death. Published data demonstrate the possibility severe suffering from COVID-19. However, these are still controversial. Methods A total 1,280 proven diagnosis COVID-19 were included our study. was confirmed all using reverse transcriptase polymerase chain reaction test nasopharyngeal swab, and based on typical computed tomography findings. Demographic data, underlying comorbidities, laboratory blood tests assessed. We assessed incidence AKI its mortality defined by survival status at discharge. Results Proteinuria identified 648 (50.6%) 371 (29.0%). Ten (2.7%) required dialysis. factors for age > 65 years, augmentation C-reactive protein, ferritin an increase values activated partial thromboplastin time. Overall, 162 hospitalized (12.7%) 111 (29.9%) did not survive. hazard ratio (HR) 3.96 (95% confidence interval, 2.83–5.54) vs. no AKI. Conclusion relatively common finding among old age, inflammatory response, severity lung involvement, disseminated intravascular coagulation. These same factors, addition to arterial hypertension, found mortality. Keywords: Acute injury, COVID-19, Hematuria, Mortality,